Genicular Artery Embolization (GAE): A Minimally Invasive Breakthrough for Chronic Knee Pain

by | Nov 18, 2025 | Genicular Artery Embolization (GAE)

Living with chronic knee pain can be life-altering, limiting mobility, independence, and quality of life. For many people, knee replacement surgery may feel like the only solution, but what if there were a minimally invasive alternative that could reduce inflammation and relieve pain without major surgery?

Dr. Stephen A. Tonks, MD, RPVI, a board-certified vascular surgeon at Premier Vascular & Vein Center in Knoxville, TN, explains an innovative treatment called Genicular Artery Embolization (GAE). Dr. Tonks shares how this cutting-edge vascular procedure is helping patients find lasting relief from knee inflammation and osteoarthritis pain, especially those who aren’t yet ready or eligible for knee replacement.

What Is Genicular Artery Embolization (GAE)?

“Genicular artery embolization is a newer technology that we use to treat inflamed arteries around the knee. These are called the geniculate arteries,” explains Dr. Tonks.

GAE targets the small blood vessels that become inflamed and contribute to chronic knee pain. By reducing blood flow to these overactive vessels, the procedure helps decrease inflammation and discomfort caused by osteoarthritis or other degenerative knee conditions.

The Benefits of GAE

“The benefit to this procedure,” says Dr. Tonks, “is that it can often truncate the inflammatory cascade, or clip off the little inflamed branches that are causing a lot of the knee inflammation.”

Because GAE is performed through a tiny catheter inserted into the blood vessels, patients typically experience:

  • Less pain and inflammation in the knee joint
  • Quick recovery times (often same-day discharge)
  • Minimal downtime compared to surgery
  • No general anesthesia or large incisions

How GAE Works

“In geniculate artery embolization,” Dr. Tonks explains, “we are occluding the tiny branches that shouldn’t be there, branches that have developed over time from inflammation. By closing off these microscopic vessels, we can help reduce the inflammation that’s feeding the loop of pain.”

Using advanced imaging guidance, vascular surgeons identify and block these abnormal vessels with microscopic particles. This restores more normal circulation patterns and helps calm the chronic inflammation driving knee pain.

Who Is a Candidate for GAE?

“Some patients who aren’t candidates for knee replacement are excellent candidates for this,” Dr. Tonks says. “And some patients who are too young, or just aren’t ready for knee replacement yet, may qualify as well.”

Ideal candidates include people with:

  • Chronic knee pain from osteoarthritis or inflammation
  • Persistent pain after knee replacement
  • Limitations that make them poor surgical candidates

How Soon Does GAE Work?

“Some people feel better shortly after the procedure—hours to a day,” Dr. Tonks notes. “For others, it can take a few weeks to notice significant improvement.”

While GAE isn’t designed to restore lost motion or repair structural damage, it can be highly effective for reducing inflammation and improving comfort in early to moderate arthritis.

A Minimally Invasive Option for Lasting Relief

Genicular Artery Embolization represents a powerful new option for managing chronic knee pain without the need for invasive surgery. As Dr. Tonks and the vascular specialists at Premier Vascular & Vein Center continue to offer leading-edge treatments, East Tennesseans have access to some of the most advanced vascular and endovascular care available.

If you’re struggling with persistent knee pain and want to find out if Genicular Artery Embolization (GAE) is right for you, we invite you to contact Premier Vascular & Vein Center.

📞 Call (865) 588-8229 or visit premiervascularveincenter.com/book-online/ to schedule your consultation today.